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Accession IconGSE107865

PBMC gene expression from Crohn's disease patients before Infliximab therapy.

Organism Icon Homo sapiens
Sample Icon 21 Downloadable Samples
Technology Badge Icon Affymetrix Clariom S Human array (clariomshuman)

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Description
About 40% IBD patients treated with anti-TNF antibodies do not respond to therapy. Baseline biomarkers of response are therefore of interest. By combining computational deconvolution of gene expression and meta-analysis approaches we identified cellular biomarkers in tissue (validated in 2 cohorts by IHC of biopsies), and investigated associated gene biomarkers in blood. This dataset provides data from the validation cohort III (blood).
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22

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