A vitamin E- supplemented antioxidant diet interferes with the acute adaptation of the liver to physical exercise in mice

Objective: Physical exercise and vitamin E are considered effective treatments of nonalcoholic fatty liver and other metabolic diseases. However, vitamin E has also been shown to interfere with the adaptation to exercise training, in particular for the skeletal muscle. Here, we studied the hypothesis that vitamin E also interferes with the metabolic adaptation of the liver to acute exercise.

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Hoene M, Irmler M, Beckers J, Hrabě de Angelis M, Häring HU, Weigert C