Identification of differentially expressed genes between control and PIK3CD GOF human activated transitional B cells
Homo sapiens
8 Downloadable Samples
Affymetrix Clariom S Human array (clariomshuman)
Submitter Supplied Information
Description
IL-21 induces B cell activation, and differentiation into antibody-secreting plasmblasts in vitro. This process is compromised in transitional B cells to gain of function mutations in PIK3CD