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Accession IconGSE116999

Identification of differentially expressed genes between control and PIK3CD GOF human activated transitional B cells

Organism Icon Homo sapiens
Sample Icon 8 Downloadable Samples
Technology Badge Icon Affymetrix Clariom S Human array (clariomshuman)

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IL-21 induces B cell activation, and differentiation into antibody-secreting plasmblasts in vitro. This process is compromised in transitional B cells to gain of function mutations in PIK3CD
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