Irinotecan-induced gene expression changes in the rat intestine

GSE11722

Rattus norvegicus

30 Downloadable Samples

Affymetrix Rat Genome 230 2.0 Array (rat2302)

Submitter Supplied Information

Description

The regional specificity and timing of gene activation following chemotherapy, and how this relates to subsequent mucositis development is currently unknown. The aim of the study was therefore to determine the early time course of gene expression changes along the gastrointestinal tract (GIT) of the DA rat following irinotecan treatment, so as to provide an insight into the genetic component of mucositis.

PubMed ID

17594691

Publication Title

Gene expression analysis of multiple gastrointestinal regions reveals activation of common cell regulatory pathways following cytotoxic chemotherapy.

Total Samples

Submitter’s Institution

Royal Adelaide Hospital

Authors

Bowen JM, Gibson RJ, Tsykin A, Stringer AM, Logan RM, Keefe DM

Source Repository

Gene Expression Omnibus (GEO)

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