Common activation of RAS_MAPK pathway in serous LMP tumours

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GSE12172

Homo sapiens

83 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Expression profile of 30 LMP tumours and 60 Serous tumours were compared to identify the biolgical pathways specific to these groups. Genotyping was done to identify the mutations potentially causing these phenotypes

PubMed ID

19010816

Publication Title

Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.

Total Samples

Submitter’s Institution

PeterMacCallum Cancer Centre

Authors

Anglesio MS, Arnold JM, George J, Tinker AV, Tothill R, Waddell N, Simms L, Locandro B, Fereday S, Traficante N, Russell P, Sharma R, Birrer MJ, AOCS Study Group., deFazio A, Chenevix-Trench G, Bowtell DD

Source Repository

Gene Expression Omnibus (GEO)

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