Changes in cardiac transcription profiles following off-pump coronary revascularization surgery

GSE12485

Homo sapiens

9 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

To investigate changes in cardiac transcription profiles caused by off-pump cardiac surgery, we collected myocardial samples, prior and after grafting, from patients undergoing off-pump coronary revascularization surgery. The transcriptional profile of the mRNA in these samples was measured with gene array technology. Changes in transcriptional profiles can be correlated with the stress response of heart to off-pump surgery.

PubMed ID

20332183

Publication Title

Off-pump coronary artery bypass surgery is associated with fewer gene expression changes in the human myocardium in comparison with on-pump surgery.

Total Samples

Submitter’s Institution

University of Bristol

Authors

Ghorbel MT, Cherif M, Mokhtari A, Bruno VD, Caputo M, Angelini GD

Source Repository

Gene Expression Omnibus (GEO)

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