Genetic analysis of radiation-induced changes in human gene expression

We used microarrays to measure the expression levels of genes in irradiated immortalized B cells, lymphoblastoid cells, from members of Centre d'Etude du Polymorphisme Humain (CEPH) Utah pedigrees. Data were collected for cells at baseline and 2 hour and 6 hour after exposure to 10 Gy of ionizing radiation (IR).

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Smirnov DA, Morley M, Shin E, Spielman RS, Cheung VG