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Accession IconGSE135172

The role of stretch, tachycardia and sodium-calcium exchanger in induction of early cardiac remodeling

Organism Icon Rattus norvegicus
Sample Icon 18 Downloadable Samples
Technology Badge Icon Affymetrix Rat Gene 2.0 ST Array (ragene20st)

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Accute stretch and tachycardia are capable of inducing pathological excitation transcription coupling - an early invent before structural cardiac remodeling which transitions to heart failure. The sodium calcium exchanger is a key player in maintaining calcium homeostasis and is implicated in pathological signaling during heart failure.
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