Drosha or DGCR8 knockdown effects on mRNA levels in HeLa

GSE13639

Homo sapiens

12 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Anaysis of mRNA changes in HeLa cells following knockdown of Drosha or DGCR8. Drosha is a nuclear RNase III that carries out microRNA (miRNA) processing by cleaving primary microRNA transcript (pri-miRNA). DGCR8 is an essential co-factor of Drosha.

PubMed ID

19135890

Publication Title

Posttranscriptional crossregulation between Drosha and DGCR8.

Total Samples

Submitter’s Institution

Seoul National University

Authors

Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, Yang WY, Haussler D, Blelloch R, Kim VN

Source Repository

Gene Expression Omnibus (GEO)

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