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Accession IconGSE15498

Genome-wide Profiling of Gene Expression in a New Rat Model of Cholangiocarcinoma Progression Mimicking the Human Cancer

Organism Icon Rattus norvegicus
Sample Icon 21 Downloadable Samples
Technology Badge Icon Affymetrix Rat Genome 230 2.0 Array (rat2302)

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Description
Validation of preclinical models of intrahepatic cholangiocarcinoma progression that reliably recapitulate altered molecular features of the human disease would provide an important resource for suggesting and testing of novel target-based therapies against this devastating cancer. In this study, comprehensive gene expression profiling in a novel orthotopic rat model of intrahepatic cholangiocarcinoma progression was carried out in an effort to identify potential therapeutic targets relevant to the progressive human cancer.
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21
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