PBMCs exposed to the Mycobacterium tuberculosis H37Ra strain

Human peripheral blood mononuclear cells were cultured in presence of H37Ra strain at 37oC, 5%CO2. Cellular aggregates were collected at 24h, and RNA extracted and hybridized to Affymetrix microarrays (HG-U133). Raw data from microarray experiments was analyzed with dCHIP and SAM programs to determine the significance of changes at the biological context.

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Reyes N, Bettin A, Reyes I, Geliebter J