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Accession IconGSE17050

Gene expression profiling in Wistar male rat left ventricle with chronic and severe aortic valve regurgitation

Organism Icon Rattus norvegicus
Sample Icon 10 Downloadable Samples
Technology Badge IconIllumina ratRef-12 v1.0 expression beadchip

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Description
Aortic valve regurgitation (AR) imposes a severe volume overload to the left ventricle (LV) which results in dilation, eccentric hypertrophy and eventually loss of function. Little is known about the impact of AR on LV gene expression. We therefore conducted a gene expression profiling study in the LV of male Wistar rats with chronic (9 months) and severe AR.
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