Deciphering the Wnt-dependent gene signature in colorectal cancer cells

GSE18560

Homo sapiens

12 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Microarray-based gene expression data were generated from RNA from Ls174T colorectal carcinoma cell lines in which Wnt-dependent transcriptional activity can be abrogated by inducible overexpression of a dominant-negative form of Tcf4 or siRNA against -catenin.

PubMed ID

21914722

Publication Title

Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes.

Total Samples

Submitter’s Institution

Academic Medical Centre, University of Amsterdam

Authors

Mokry M, Hatzis P, Schuijers J, Lansu N, Ruzius FP, Clevers H, Cuppen E

Source Repository

Gene Expression Omnibus (GEO)

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