Expression data from static and cyclic stretched porcine aortic heart valves

GSE21663

Sus scrofa

23 Downloadable Samples

Affymetrix Porcine Genome Array (porcine)

Submitter Supplied Information

Description

We explored the hypothesis that Serotonin (5HT) receptor signaling, that can be enhanced with 5HT transporter blockade with Fluoxetine (Fluox), in the aortic valve may vary based upon the biomechanical activity of the aortic valve leaflet.

PubMed ID

21718840

Publication Title

Aortic valve cyclic stretch causes increased remodeling activity and enhanced serotonin receptor responsiveness.

Total Samples

Submitter’s Institution

Children's Hospital of Philadelphia

Authors

Balachandran K, Bakay MA, Connolly JM, Zhang X, Yoganathan AP, Levy RJ

Source Repository

Gene Expression Omnibus (GEO)

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