Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

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GSE22011

Homo sapiens

15 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

We tested the hypothesis that increasing matrix stiffness on which normal human lung fibroblasts are grown promotes the expression of a fibrogenic cellular transcriptomic program.

PubMed ID

20733059

Publication Title

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression.

Total Samples

Submitter’s Institution

Boston Children's Hospital

Authors

Liu F, Mih JD, Shea BS, Kho AT, Sharif AS, Tager AM, Tschumperlin DJ

Source Repository

Gene Expression Omnibus (GEO)

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