Primary human erythroid progenitor cells HDAC1 and HDAC2 shRNA knockdown samples

GSE22366

Homo sapiens

14 Downloadable Samples

Affymetrix HT Human Genome U133A Array (hthgu133a), Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

Gene expression profiling was performed on primary human erythroid progenitor cells expressing a control shRNA (luciferase), two different HDAC1 shRNAs, and two different HDAC2 shRNAs.

PubMed ID

20616024

Publication Title

Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease.

Total Samples

Submitter’s Institution

Dana-Farber Cancer Institute

Authors

Bradner JE, Mak R, Tanguturi SK, Mazitschek R, Haggarty SJ, Ross K, Chang CY, Bosco J, West N, Morse E, Lin K, Shen JP, Kwiatkowski NP, Gheldof N, Dekker J, DeAngelo DJ, Carr SA, Schreiber SL, Golub TR, Ebert BL

Source Repository

Gene Expression Omnibus (GEO)

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