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Accession IconGSE24790

Neonatal beta cells lack the specialized metabolic phenotype of mature beta cells

Organism Icon Rattus norvegicus
Sample Icon 4 Downloadable Samples
Technology Badge Icon Affymetrix Rat Genome U34 Array (rgu34a)

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Description
Fetal and neonatal beta cells have poor glucose-induced insulin secretion and only gain robust glucose responsiveness several weeks after birth. This unresponsiveness may be due to a generalized immaturity of the metabolic pathways normally found in beta cells.
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