Down-regulation of BLIMP1-alpha by the EBV oncogene, LMP1, disrupts the plasma cell differentiation program and prevents viral replication in B cells

GSE27670

Homo sapiens

6 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

In this study, we have investigated the effect of BLIMP1 on gene expression, cell differentiation and pathogenesis in normal human GC B cells using a non-viral vector based system

PubMed ID

21411757

Publication Title

Down-regulation of BLIMP1α by the EBV oncogene, LMP-1, disrupts the plasma cell differentiation program and prevents viral replication in B cells: implications for the pathogenesis of EBV-associated B-cell lymphomas.

Total Samples

Submitter’s Institution

University of Birmingham

Authors

Vrzalikova K, Vockerodt M, Leonard S, Bell A, Wei W, Schrader A, Wright KL, Kube D, Rowe M, Woodman CB, Murray PG

Source Repository

Gene Expression Omnibus (GEO)

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