Differential regulation of Twist1-responsive genes in 4T1 cells

GSE29754

Mus musculus

15 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

Twist1 variants including wildtype Twist1, a non-phosphorylatable mutant Twist1/S42A and a phospho-mimicking mutant Twist1/S42D were expressed in 4T1 cells in which the endogenous Twist1 was depleted.

PubMed ID

22585995

Publication Title

Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes.

Total Samples

Submitter’s Institution

Friedrich Miescher Institute for Biomedical Research

Authors

Xue G, Restuccia DF, Lan Q, Hynx D, Dirnhofer S, Hess D, Rüegg C, Hemmings BA

Source Repository

Gene Expression Omnibus (GEO)

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