p53-dependent transcription program in HepG2 cells

GSE30137

Homo sapiens

12 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

In order to obtain a global picture regarding regulation of p53 in liver cells we used HepG2 hepatoma cells.We created two isogenic sub-cultures of HepG2 cells with altered expression of p53.

PubMed ID

23054612

Publication Title

Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53.

Total Samples

Submitter’s Institution

The Weizmann Institute of Science

Authors

Goldstein I, Rivlin N, Shoshana OY, Ezra O, Madar S, Goldfinger N, Rotter V

Source Repository

Gene Expression Omnibus (GEO)

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