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GSE30315
DMSO control and DZNep treated MOLM-14 cells
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Homo sapiens
4 Downloadable Samples
Affymetrix Human Gene 1.0 ST Array (hugene10st)
Submitter Supplied Information
Description
We demonstrated that 3-Deazaneplanocin A (DZNep), a histone methyltransferase inhibitor, induce robust apoptosis in AML cells through increased ROS production and ER stress.
PubMed ID
21734239
Publication Title
The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML.
Total Samples
4
Submitter’s Institution
Cancer Science Institute Singapore
Authors
Zhou J
,
Bi C
,
Cheong LL
,
Mahara S
,
Liu SC
,
Tay KG
,
Koh TL
,
Yu Q
,
Chng WJ
Source Repository
Gene Expression Omnibus (GEO)
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