Expression analysis of G9C8 clone and NOD.G9C8 tg CTLs

Diabetogenic CD8+ G9C8 clone cells and the T cells from a transgenic mouse bearing the same TCR as the clone, displayed differences in their ability to induce disease in vivo.Microarray analysis was done to identify the molecular basis for such differences between the two sets of CD8 T cells.

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Varanasi V, Avanesyan L, Schumann DM, Chervonsky AV