Effect of Th-POK deficiency on global gene expression in liver Va14i NKT cells

We sought to identify genes regulated by the transcription factor Th-POK (Zbtb7b) in liver Va14i NKT cells, by RNA microarray analysis of global gene expression in Va14i NKT cells from mice homozygous for the Th-POK-inactivating hd point mutation as compared with the same cell population isolated from heterozygous or wild-type age-matched mice.

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Engel I, Zhao M, Kappes D, Taniuchi I, Kronenberg M