brain expression data from adult mice exposed to ethanol at postnatal day 4 and 7

The developing brain is particularly sensitive to ethanol during the brain growth spurt or synaptogenesis (third human trimester equivalent). This has been shown to lead to abnormal brain development and behavioural changes in the adult mouse that are relevant to those seen in humans with fetal alcohol spectrum disorders (FASD). We evaluated the long-term (postnatal day 60 young adult) gene expression changes that occur in the brain due to ethanol exposure during synaptogenesis.

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Laufer BI, Mantha K, Kleiber ML, Diehl EJ, Addison SM, Singh SM