KGF effects on cutaneous SCC cells

GSE34652

Homo sapiens

8 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

Keratinocyte growth factor (KGF, fibroblast growth factor-7) is a fibroblast-derived mitogen, which stimulates proliferation of epithelial cells. The expression of KGF by dermal fibroblasts is induced following injury and it promotes wound repair. However, the role of KGF in cutaneous carcinogenesis and cancer progression is not known. We have examined the role of KGF in progression of squamous cell carcinoma (SCC) of the skin.

PubMed ID

22427941

Publication Title

Keratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells.

Total Samples

Submitter’s Institution

University of Turku, Turku University Hospital

Authors

Toriseva M, Ala-aho R, Peltonen S, Peltonen J, Grénman R, Kähäri VM

Source Repository

Gene Expression Omnibus (GEO)

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