Expression data from murine fibroblasts overexpressing Fbxl10

Posttranslational modifications on histone tails control gene expresssion levels in an either positive or negative way. Therefore enzymes which modifiy the modifications on the histon tails, like histone demethylases, are able to strictly regulate the transcriptom.

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Janzer A, Stamm K, Becker A, Zimmer A, Buettner R, Kirfel J