Expression from early pre-hematopoietic progenitors from mouse embryo

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GSE35395

Mus musculus

6 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

Hematopoietic Stem Cells (HSC) are originated during embryonic development from endothelial-like cells located in the ventral side of the dorsal aorta around day E10-12 of murine development. This region is called AGM for Aorta/Gonad/Mesonephros and refers to the tissues around the hemogenic aorta. Cells that emerge from the endothelium and show hematopoietic traits can be distinguished by the expression of the c-kit receptor and finally acquire the CD45 marker.

PubMed ID

22802352

Publication Title

Hematopoietic stem cell development requires transient Wnt/β-catenin activity.

Total Samples

Submitter’s Institution

Institut Hospital del Mar d'Investigacions Mdiques

Authors

Ruiz-Herguido C, Guiu J, D'Altri T, Inglés-Esteve J, Dzierzak E, Espinosa L, Bigas A

Source Repository

Gene Expression Omnibus (GEO)

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