Effects of TCDD on differentiating NHEKs

GSE36796

Homo sapiens

8 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

TCDD increased expression of numerous differentiation specific genes and decreased expression of numerous genes involved in mitochondrial health and redox homeostasis

PubMed ID

23152189

Publication Title

2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated production of reactive oxygen species is an essential step in the mechanism of action to accelerate human keratinocyte differentiation.

Total Samples

Submitter’s Institution

University of Memphis

Authors

Kennedy LH, Sutter CH, Leon Carrion S, Tran QT, Bodreddigari S, Kensicki E, Mohney RP, Sutter TR

Source Repository

Gene Expression Omnibus (GEO)

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