Expression of Human nave B cell priming for plasma cell differentiation

GSE36975

Homo sapiens

24 Downloadable Samples

Illumina HumanHT-12 V4.0 expression beadchip

Submitter Supplied Information

Description

To explore events that govern the differentiation of human nave B cells (NBCs) into memory B cells and plasma cells (PCs), we designed an in vitro 2-step culture model leading non-switched NBC precursors to differentiate into two cell compartments: CD20loCD38hi and CD20+CD38+.

PubMed ID

22634617

Publication Title

IL-2 requirement for human plasma cell generation: coupling differentiation and proliferation by enhancing MAPK-ERK signaling.

Total Samples

Submitter’s Institution

Rennes University Hospital

Authors

Le Gallou S, Caron G, Delaloy C, Rossille D, Tarte K, Fest T

Source Repository

Gene Expression Omnibus (GEO)

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