Gene expression profile of PBMCs in response to metreleptin treatment at different time points.

GSE36990

Homo sapiens

57 Downloadable Samples

Affymetrix HT Human Genome U133B Array (hthgu133b), Affymetrix HT Human Genome U133A Array (hthgu133a)

Submitter Supplied Information

Description

we evaluated the modulation of gene expression profile in PBMCs from patients with hypotalamic amenorrhea. We have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed upon metreleptin treatment at different time points, week 12, 24 and 36.

PubMed ID

23382191

Publication Title

Selective capacity of metreleptin administration to reconstitute CD4+ T-cell number in females with acquired hypoleptinemia.

Total Samples

114

Submitter’s Institution

University of Helsinki

Authors

Matarese G, La Rocca C, Moon HS, Huh JY, Brinkoetter MT, Chou S, Perna F, Greco D, Kilim HP, Gao C, Arampatzi K, Wang Z, Mantzoros CS

Source Repository

Gene Expression Omnibus (GEO)

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