Expression analysis of control and low protein fed mouse offspring subsequently treated with multiple low doses of STZ

Low protein (LP) during gestation leads to low birth weight and poor fetal growth, with altered islet development and glucose intolerance in adulthood. Additionally, LP offspring fail to regenerate their -cells following depletion with streptozotocin (STZ), in contrast to control-fed offspring that are capable of -cell regeneration.

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Cox AR, Beamish CA, Carter DE, Arany EJ, Hill DJ