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Accession IconGSE41185

Potentiation of regulatory T cell stability and function via a neuropilin-1:semaphorin-4a axis

Organism Icon Mus musculus
Sample Icon 8 Downloadable Samples
Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302), Affymetrix HT MG-430 PM Array Plate (htmg430pm)

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Description
Regulatory T cells (Treg) represent a critical immunoregulatory component of the immune system. The signals that maintain Treg stability and potentiate their function remain obscure. Here we show that the immune cell surface ligand semaphorin-4a (Sema4a)
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