Expression data from dsDNA-stimulated mouse embryonic fibroblasts

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GSE42803

Mus musculus

16 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

Transfection of dsDNA into many mammalian cell types indues the production of type I interferons and interferon-stimulated genes. We performed an siRNA screen to identify genes involved in this innate immune response, and identified Abcf1.

PubMed ID

23263557

Publication Title

Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.

Total Samples

Submitter’s Institution

Broad Institute

Authors

Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N

Source Repository

Gene Expression Omnibus (GEO)

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