Expression data from human multiple myeloma cells with or without IRE1-XBP1 silencing

GSE44968

Homo sapiens

8 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

We used microarrays to develop gene signatures for XBP1 and IRE1 in myeloma cells to explore the role of this UPR/differentiation pathway in proteasome inhibitor resistance.

PubMed ID

24029229

Publication Title

Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma.

Total Samples

Submitter’s Institution

University Health Network, University of Toronto, Princess Margaret Cancer Centre

Authors

Leung-Hagesteijn C, Erdmann N, Cheung G, Keats JJ, Stewart AK, Reece DE, Chung KC, Tiedemann RE

Source Repository

Gene Expression Omnibus (GEO)

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