Response of mammary tissue to high-LET HZE particle (Silicon ions) radiation or low-LET gamma-rays

GSE48392

Mus musculus

36 Downloadable Samples

Affymetrix Mouse Gene 1.1 ST Array (mogene11st)

Submitter Supplied Information

Description

Transcriptional profiling of mammary tissue irradiated at 10 weeks of age with either 100 cGy sparsely ionizing gamma-rays, or 10 cGy or 30 cGy densely ionizing radiation (350 MeV/amu Si). Mammary tissue was collected 1 weeks, 4 weeks, and 12 weeks post-irradiation.

PubMed ID

24038768

Publication Title

Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors.

Total Samples

Submitter’s Institution

Lawrence Berkeley National Laboratory

Authors

Tang J, Fernandez-Garcia I, Vijayakumar S, Martinez-Ruis H, Illa-Bochaca I, Nguyen DH, Mao JH, Costes SV, Barcellos-Hoff MH

Source Repository

Gene Expression Omnibus (GEO)

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