RNA-Seq and expression microarray highlight different aspects of the fetal amniotic fluid transcriptome [microarray]

The second trimester fetal transcriptome can be assessed based on cell-free RNA found within the amniotic fluid supernatant. The objective of this study was to compare the suitability of two technologies for profiling the human fetal transcriptome: RNA-Seq and expression microarray. Comparisons were based on total numbers of gene detected, rank-order gene expression, and functional genomic analysis.

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Zwemer LM, Hui L, Wick HC, Bianchi DW