Effect of Alloantibody and Complement on Endothelial Cells

GSE50112

Homo sapiens

36 Downloadable Samples

Illumina HumanHT-12 V4.0 expression beadchip

Submitter Supplied Information

Description

Examine the possible pro-inflammatory gene effects of alloantibody and complement on endothelial cells

PubMed ID

24045046

Publication Title

Alloantibody and complement promote T cell-mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells.

Total Samples

Submitter’s Institution

Yale University School of Medicine

Authors

Jane-Wit D, Manes TD, Yi T, Qin L, Clark P, Kirkiles-Smith NC, Abrahimi P, Devalliere J, Moeckel G, Kulkarni S, Tellides G, Pober JS

Source Repository

Gene Expression Omnibus (GEO)

GSM1216854

Complement-Inactivated PRA Serum Treated HUVEC Replicate 3 [7509301029_C]

huvec

heat inactivated pra 55c

GSM1216853

Complement-Inactivated PRA Serum Treated HUVEC Replicate 2 [7509301029_B]

huvec

heat inactivated pra 55c

GSM1214297

PRA Serum Treated HUVEC Replicate 2 [7165895070_H]

huvec

pra=high panel reactive antibody serum from pre-transplant patients

GSM1214295

Vehicle Treated HUVEC Replicate 3 [7165895070_F]

huvec

vehicle=gelatin veronal buffer

GSM1216861

Normal Non-PRA Serum Treated HUVEC Replicate 1 [7509301029_J]

huvec

non-pra=low panel reactive antibody serum from healthy donors

GSM1216857

Vehicle Treated HUVEC Replicate 3 [7509301029_F]

huvec

vehicle=gelatin veronal buffer

GSM1214281

Vehicle Treated HUVEC Replicate 1 [7165895087_D]

huvec

vehicle=gelatin veronal buffer

GSM1214285

PRA Serum Treated HUVEC Replicate 2 [7165895087_H]

huvec

pra=high panel reactive antibody serum from pre-transplant patients

GSM1214284

PRA Serum Treated HUVEC Replicate 1 [7165895087_G]

huvec

pra=high panel reactive antibody serum from pre-transplant patients

GSM1214282

Vehicle Treated HUVEC Replicate 2 [7165895087_E]

huvec

vehicle=gelatin veronal buffer