Gene expression in aortic aneurysms associated with tricuspid and bicuspid valves

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GSE5180

Homo sapiens

25 Downloadable Samples

Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

Patients with bicuspid aortic valve (BAV) have increased risk of thoracic ascending aortic aneurysm (AscAA) and dissection compared to those with a normal tricuspid aortic valve (TAV). The present study was undertaken to evaluate whether differences in gene expression exist in aortas from BAV and TAV patients with AscAA.

PubMed ID

17502243

Publication Title

Elevated expressions of osteopontin and tenascin C in ascending aortic aneurysms are associated with trileaflet aortic valves as compared with bicuspid aortic valves.

Total Samples

Submitter’s Institution

Mayo Clinic

Authors

Majumdar R, Miller DV, Ballman KV, Unnikrishnan G, McKellar SH, Sarkar G, Sreekumar R, Bolander ME, Sundt TM 3rd

Source Repository

Gene Expression Omnibus (GEO)

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