Cdk8, Cyclin C, Med12 or Med13 depletion effect on gene expression in Drosophila S2 cells

GSE52343

Drosophila melanogaster

22 Downloadable Samples

Affymetrix Drosophila Genome 2.0 Array (drosophila2)

Submitter Supplied Information

Description

Expression profiling following depletion of Mediator Cdk8 module subunits Cdk8, Cyclin C (CycC), Med12 and Med13 72 hours after dsRNA treatment of Drosophila melanogaster S2 cells. Results provide insight into the role of individual Cdk8 module subunits in regulation of transcription.

PubMed ID

24778181

Publication Title

Cyclin-dependent kinase 8 module expression profiling reveals requirement of mediator subunits 12 and 13 for transcription of Serpent-dependent innate immunity genes in Drosophila.

Total Samples

Submitter’s Institution

University of Helsinki

Authors

Kuuluvainen E, Hakala H, Havula E, Sahal Estimé M, Rämet M, Hietakangas V, Mäkelä TP

Source Repository

Gene Expression Omnibus (GEO)

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