The Demethylase JMJD2C/KDM4C Localizes to H3K4me3 Positive Transcription Start Sites (Affymetrix microarray analysis)

GSE53892

Homo sapiens

12 Downloadable Samples

Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Submitter Supplied Information

Description

We have mapped transcriptional changes after depletion of the histone demethylases JMJD2C/GASC1/KDM4C and JMJD2A/KDM4A alone or in combination in the esophageal squamous carcinoma cell line, KYSE150. The KYSE150 cell line contains an amplification of the JMJD2C locus.

PubMed ID

24396064

Publication Title

The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development.

Total Samples

Submitter’s Institution

BRIC

Authors

Pedersen MT, Agger K, Laugesen A, Johansen JV, Cloos PA, Christensen J, Helin K

Source Repository

Gene Expression Omnibus (GEO)

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