Dose-response modeling of early molecular and cellular key events in CAR-mediated hepatocarcinogenesis pathway

Male and female CD-1 mice were administered dietary Phenobarbital for 2 or 7 days. In-life, enzyme activity, cell proliferation, genomic analysis, and Bench-mark dose modeling was carried out.

96

Geter DR, Bhat VS, Gollapudi BB, Sura R, Hester SD