Global murine pulmonary response to highly and less virulent influenza A (H3N2) virus infections at 12, 48 and 96 h post-infection

GSE55994

Mus musculus

18 Downloadable Samples

Illumina mouseRef-8 v1.1 expression beadchip

Submitter Supplied Information

Description

Array analysis of total lung RNAs from female BALB/c mice collected at 12, 48 and 96 h post-infection with highly and less virulent influenza A (H3N2) viruses. Viruses (designated as LVI and HVI) were derived from influenza strain virus A/Aichi/2/68 (Aichi68). LVI is Aichi68 propagated in eggs, and HVI is mouse adapted Aichi68.

PubMed ID

21874528

Publication Title

Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines.

Total Samples

Submitter’s Institution

National University of Singapore (NUS)

Authors

Ivan FX, Rajapakse JC, Welsch RE, Rozen SG, Narasaraju T, Xiong GM, Engelward BP, Chow VT

Source Repository

Gene Expression Omnibus (GEO)

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