Effect of somatostatin knockout on sexually dimorphic hepatic gene expression

GSE56520

Mus musculus

12 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

The liver is one of the most sexually dimorphic organs as measured by gene expression differences. About 80% of the sexually dimorphic genes are known to be regulated by growth hormone (GH). Somatostatin (SST) inhibits the release of GH.

PubMed ID

25551181

Publication Title

Somatostatin is essential for the sexual dimorphism of GH secretion, corticosteroid-binding globulin production, and corticosterone levels in mice.

Total Samples

Submitter’s Institution

University of Michigan

Authors

Adams JM, Otero-Corchon V, Hammond GL, Veldhuis JD, Qi N, Low MJ

Source Repository

Gene Expression Omnibus (GEO)

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