Global gene expression profile of INS1E cells, hIAPP-INS1E cells and rIAPP-INS1E cells.

GSE57573

Rattus norvegicus

6 Downloadable Samples

Affymetrix Rat Gene 2.0 ST Array (ragene20st)

Submitter Supplied Information

Description

Islet amyloid polypeptide (IAPP) is the main component of amyloid deposits in type 2 diabetic patients. Cells overexpressing the human transcript of IAPP (hIAPP) present defects in insulin secretion.

PubMed ID

25342134

Publication Title

Inhibition of BACE2 counteracts hIAPP-induced insulin secretory defects in pancreatic β-cells.

Total Samples

Submitter’s Institution

IDIBAPS

Authors

Alcarraz-Vizán G, Casini P, Cadavez L, Visa M, Montane J, Servitja JM, Novials A

Source Repository

Gene Expression Omnibus (GEO)

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