NF-kB in Tumor Initiation

GSE59545

Mus musculus

4 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

p65-/-Ras cells show delayed tumor formation in SCID mice. However, after prolonged latency, tumor formation was observed from these mice. To understand the changes of NF-kB regulated genes before and after tumor formation, RNA from p65+/+Ras, p65+/+RasTumor, p65-/-Ras, p65-/-RasTumor cells were isolated and microarray were performed.

PubMed ID

25263557

Publication Title

NF-κB functions in tumor initiation by suppressing the surveillance of both innate and adaptive immune cells.

Total Samples

Submitter’s Institution

The Ohio State University

Authors

Wang DJ, Ratnam NM, Byrd JC, Guttridge DC

Source Repository

Gene Expression Omnibus (GEO)

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