Mouse model of Endometrioid Ovarian Adenocarcinomas by conditional inactivation of PTEN and APC genes

Fifty million plaque-forming units of AdCre was injected into the right ovarian bursal cavity of 56- 70 day old female mice. Mice were euthanized 63 days later to obtain ovary tumors and normal ovary tissue. Seven individual ovarian tumors and 4 individual normal ovary samples were each assayed on an Affymetrix Mouse Genome 430 2.0 array.

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Hendrix ND, Wu R, Kuick R, Schwartz DR, Fearon ER, Cho KR