Expression microarray analysis of HaCaT epidermal keratinocyte treated with AdcaRAS/dnRAS, p53 siRNA, and/or TGF-beta

GSE60813

Homo sapiens

6 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

We demonstrate that activation of Ras and TGF- pathways strengthens the binding of p63 to its genomic sites and modulates the expression of p63 target genes.

PubMed ID

27555661

Publication Title

Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program.

Total Samples

Submitter’s Institution

University of Tokyo

Authors

Vasilaki E, Morikawa M, Koinuma D, Mizutani A, Hirano Y, Ehata S, Sundqvist A, Kawasaki N, Cedervall J, Olsson AK, Aburatani H, Moustakas A, Miyazono K, Heldin CH

Source Repository

Gene Expression Omnibus (GEO)

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