Expression data from SKOV3ip1 cells treated with MORAB-003 antibody

GSE61513

Homo sapiens

15 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

MORAB-003 significantly upregulated a number of genes involved in autophagic processing, including GABARAPL2, LC3II (MAP1LC3B), ATG3, ATG4B, and BECN1, while expression of the oncogenic factor PIK3C3 was downregulated.

PubMed ID

25416196

Publication Title

Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer.

Total Samples

Submitter’s Institution

UT MD Anderson

Authors

Wen Y, Graybill WS, Previs RA, Hu W, Ivan C, Mangala LS, Zand B, Nick AM, Jennings NB, Dalton HJ, Sehgal V, Ram P, Lee JS, Vivas-Mejia PE, Coleman RL, Sood AK

Source Repository

Gene Expression Omnibus (GEO)

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