ICI182780 effect on breast cancer cell in hypoxia

GSE61799

Homo sapiens

8 Downloadable Samples

Illumina HumanWG-6 v3.0 expression beadchip

Submitter Supplied Information

Description

The ER alpha positive breast cancer MCF7 cells were treated with ER alpha antagonist ICI182780 in normoxia and hypoxia. Extracted RNA was subject to microarray analysis. The goal of the experiment is to assess the ICI182780 effect on breast cancer cell in both normoxia and hypoxia.

PubMed ID

26598706

Publication Title

Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer.

Total Samples

Submitter’s Institution

University of Oxford

Authors

Yang J, AlTahan A, Jones DT, Buffa FM, Bridges E, Interiano RB, Qu C, Vogt N, Li JL, Baban D, Ragoussis J, Nicholson R, Davidoff AM, Harris AL

Source Repository

Gene Expression Omnibus (GEO)

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