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Accession IconGSE6300

Expression data from eye antennal imaginal disc expressing either activated Ras or secreted Spitz

Organism Icon Drosophila melanogaster
Sample Icon 5 Downloadable Samples
Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

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We have used microarrays to identify genes expressed and required for the second mitotic wave (SMW) during eye development. Eye discs expressing Spitz under the control of GMR Gal4 have no SMW as Spitz promotes G1 arrest, ectopic differentiation also occures. To control for the ectopic differentiation, Spi expressing eye antennal discs were compared to eye antennal discs expressing activated RasV12. In discs expresseding RasV12 under the control of GMRGal4 the SMW takes place normally prior to any ectopic differentiation.
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